Researchers from the Institute for Bioengineering of Catalonia in Barcelona and West China Hospital of Sichuan University have developed nanoparticles that act as medicines in their own right by restoring the brain's natural waste-removal system rather than directly targeting damaged neurons. A single injection of the supramolecular nanoparticles reduced toxic beta-amyloid protein levels in Alzheimer's model mice by 45 percent within two hours by repairing the blood-brain barrier, and elderly treated mice later performed as well as healthy young animals in memory and movement tests. The findings, published in a scientific journal and amplified by ScienceDaily in May 2026, open a new therapeutic strategy for a disease affecting tens of millions worldwide and offer a realistic pathway toward human clinical trials.

Science · May 24 · L1-L4